Wednesday, August 29

World's largest scandal

I am in a class about burden of mortality. The prof. Kirk Smith calls the total number of deaths in children < 5 years of age caused by vaccine preventable diseases as the "World's largest scandal".
I think this is probably a good description and a fantastic way to focus the world's attention on vaccine preventable diseases.

Good questions to ask:

1. Why doesn't India have cholera and typhoid vaccination programs or a Hib vaccination program?
I asked some simple questions - What do we need to know to justify the implementation of a vaccine program.

1. We need to have a vaccine that is successful in preventing the infection.
2. The disease must have high mortality/disability if people are infected. (NOTE: Pertussis,Diptheria don't have that right?)
3. We must be able to show that the cost of the vaccine is not greater than the cost of treatment or other prevention measures.
4. The vaccine must work irrespective of the load of the infectious agent
5. The agent must not have multiple strains/serotypes that making a vaccine difficult to prevent
6. How prevalent is the disease? what is the burden of disease and mortality rates?
7. Cynically, someone must have enough money to pay for the research.

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